Scientific Program

  • [Day 1] September 13 (Wed)
  • [Day 2] September 14 (Thu)
  • [Day 3] September 15 (Fri)
  • [Day 4] September 16 (Sat)

*Co-host

[Day 2] September 14 (Thu)
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
08:00 Registration
09:30-09:50 Presidential address & Genexine Award Ceremony
09:50-10:40 Plenary Lecture 1- KAI-Genexine Grand Achievement Award Lecture
ChairSeung-Woo Lee (POSTECH, Korea)
KAI-Genexine Grand Achievement Award Lecture - Regulation of T cell immunity inside and outside tumor
Sang Jun Ha (Yonsei University, Korea)
10:40-11:00 Coffee Break
11:00-12:40 Symposium 1 - T Cell Biology Symposium 2 - KAI-AKAI Education Session 1 - Multi-Omics (Korean Session)
Chair Je-Min Choi (Hanyang University, Korea)
Eun Young Choi (Seoul National University, Korea)
Chair Sung Ho Park (UNIST, Korea)
Se Jin Im (Sungkyunkwan University, Korea)
ChairSeong Kug Eo (Jeonbuk National University, Korea)
Jungsik Song (Yonsei University, Korea)
11:00-11:25 LFA-1-ICAM-1 signals for lymphocyte adhesion and differentiation: findings and puzzles 11:00-11:25 Immune-induced choriocarcinoma regression via endoplasmic reticulum aminopeptidase 2 11:00-11:25 Introduction to immunomics/
면역학을 위한 다중오믹스 소개
Ronen Alon (Weizmann Institute, Israel) Eun Lee (Virginia Commonwealth University, USA) Jaechul Lim (Seoul National University, Korea)
11:25-11:50 Engaging the immunological synapse to combat infection and cancer 11:25-11:50 Age-associated B cells: functional and phenotypic heterogeneity in SLE 11:25-11:50 Spatiotemporally Resolved Single-cell Analyses Delineate Early Esophageal Squamous Carcinogenesis/
단일세포 기반 다중오믹스 분석법의 현황
Michael Dustin (University of Oxford, UK) Sun Jung Kim (Northwell Health, USA) Jungmin Choi(Korea University, Korea)
11:50-12:15 A mechanism for helper T cell polyfunctionality in vivo 11:50-12:15 Identification of pathologic memory CD4+ T cells in human inflammatory diseases 11:50-12:15 The Use of Omics (or Multi-omics) Data in Precision Medicine for Immune-Mediated Diseases (IMD)/
면역매개 염증성 질환에서 (멀티)오믹스 데이터를 활용한 정밀 의료
Yeonseok Chung (Seoul National University, Korea) Jeong Seok Lee (KAIST, Korea) Seon-Pil Jin (Seoul National University, Korea)
12:15-12:40 Transcriptional regulation of SAP-dependent Tfh differentiation and IL-21-mediated humoral immunity 12:15-12:40 KAI-Genexine Grand Achievement Award Lecture - Tumor-associated monocytes and neutrophils: Targets for immunotherapy? 12:15-12:40 Planning an Omics Study: What should we consider?/ 오믹스 연구 계획하기: 무엇을 고려해야 할까?
Youn Soo Choi (Seoul National University, Korea) Keehoon Jung (Seoul National University, Korea) Jung U Shin (CHA University, Korea)
12:40-13:30 Luncheon Symposium 1 - Novartis Korea Luncheon Symposium 2 - Eisai Korea
ChairShin Seok Lee (Chonnam National University, Korea) ChairJin-Wuk Hur (Eulji University, Korea)
12:40-13:30 Exploring IL-17A from inflammation to bone damage 12:40-13:30 The Efficacy and Safety of Jyseleca
Seokchan Hong (University of Ulsan, Korea) Jae Hyun Jung (Korea University, Korea)
13:30-14:30 Poster Presentation (Grand Ballroom C)
14:30-14:50 Coffee Break
14:50-16:30 Symposium 3 - Infection and Vaccines
[Infection Control Convergence Medical Research Center]*, [VITAL-Korea]*
Symposium 4 - Allergic Diseases Education Session 2 - FACS (Korean Session)
Chair Nam Hyuck Cho (Seoul National University, Korea)
Ji Eun Oh (KAIST, Korea)
Chair Suk-Jo Kang (KAIST, Korea)
Lark Kyun Kim (Yonsei University, Korea)
Chair Sang-Myeong Lee (Chungbuk National University, Korea)
14:50-15:15 mTOR regulates CD8 T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection 14:50-15:15 Remaining uncertainties about the dose and timing of onset of allergenic food introduction in infants to prevent food allergy 14:50-15:40 Applications of flow cytometry in immunology/ 면역학에서 유세포 분석기를 이용한 분석법
Koichi Araki (University of Cincinnati, USA) Michael Perkin (University of London, UK)
15:15-15:40 Evolution of SARS-CoV-2 15:15-15:40 Exploiting pathways and Immune targets that regulate allergic lung inflammation
Kei Sato (University of Tokyo, Japan) Omid Akbari (University of Southern California, USA) So-Hee Hong (Ewha Womans University, Korea)
15:40-16:05 7 year follow-up study on antibody responses against zoonotic coronaviruses in Korean MERS cohort 15:40-16:05 Skin-resident Treg cells in allergen-specific immunotherapy 15:40-16:30 Advancing Targeted Single Cell Proteomics: CyTOF/ 단일세포 표적 단백 분석, FACS 그 이후: CyTOF
Nam Hyuck Cho (Seoul National University, Korea) Chang Ook Park (Yonsei University, Korea)
16:05-16:30 Fc-fused interleukin-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells 16:05-16:30 Induction of natural IgE by glucocorticoids
Seung-Woo Lee (POSTECH, Korea) Jaechul Lim (Seoul National University, Korea) Hyun Je Kim (Seoul National University, Korea)
16:30-16:50 Coffee Break
16:50-17:40 Plenary Lecture 2    
ChairHye Young Kim (Seoul National University, Korea)
16:50-17:40 Innate Lymphoid Cells and antibodies in fighting inflammations and infections of the respiratory tract.
Hergen Spits (Amsterdam UMC, Netherlands)

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[Day 1] September 13(Wed)    KAI-Songdo ImmunoBio Forum
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
09:00 Registration
09:30-09:35 개회사 - 전창덕(대한면역학회 회장)
09:35-09:40 축사 - 김진용 (인천경제자유구역청장)
09:40-09:45 인사말 - 홍기종 (신변종 감염병 mRNA백신 사업단 단장)
09:45-10:35 Plenary Lecture - Post Pandemic 시대의 백신개발 (신변종 감염병 mRNA백신 사업단)
Chair박영민(세종대)
09:45-10:35  mRNA vaccines: potential for global public health
송만기(국제백신연구소)
10:35-10:45 Break
10:45-12:25 Session 1 - 국내 mRNA백신 개발 현황 (신변종 감염병 mRNA백신 사업단)
Chair홍기종(신변종 감염병 mRNA백신 사업단)
10:45-11:10 A novel 5’ cap analogue-driven COVID-19 mRNA-LNP vaccine induced safe and efficient protection against SARS-CoV-2 infections/
양주성(에스티팜)
11:10-11:35 Development of mRNA vaccine platform: Based on the experience of COVID-19 mRNA vaccines/ COVID-19 mRNA 백신 경험을 바탕으로 한 mRNA 백신 플랫폼 개발
김석현(아이진)
11:35-12:00 Development of an mRNA-based tuberculosis vaccine/ mRNA 플랫폼을 이용한 결핵백신 개발
이진희(큐라티스)
12:00-12:25 A new platform of microneedle array patch for mRNA vaccine development/ mRNA 백신 개발을 위한 새로운 마이크로니들 플랫폼 기술
김주영(쿼드메디슨)
12:25-13:30 Break
13:30-15:10 Session 2 - 국내 mRNA백신 관련 기술 동향 (신변종 감염병 mRNA백신 사업단)
Chair송윤재(가천대)
13:30-13:55 mRNA Access: Open Access Solution for Emerging and Neglected Infectious Diseases Research/ mRNA Access: 신변종 감염병 대응 연구를 위한 모더나 오픈 엑세스 솔루션
이한솔(모더나코리아)
13:55-14:20 Next-generation mRNA design – increasing mRNA potency with a new cap analog
ChanFeng Zhao(TriLink USA)
14:20-14:45 Microfluidics Innovation: LNP formulation for gene and drug delivery/ 미세유체기술 적용 유전체 및 약물 전달을 위한 LNP제조 기기 및 기술 소개
고정상(엔파티클)
14:45-15:10 Development of GMP-grade production technology of essential enzymes for mRNA vaccines/ GMP급 mRNA 백신 생산용 필수효소 생산기술개발
신용걸(엔지노믹스)
15:10-15:30 Break
15:30-17:00 Session 3 - 국립면역학연구원 설립 공청회 (대한면역학회)
Chair박영민(세종대)
15:30-15:45 세계적 선도 면역학연구소의 사례
Minsoo Kim(University of Rochester)
15:45-15:55 국가 바이오 정책 현황 및 추진방향
이근재(메디팁)
15:55-16:05 국립면역학연구원 홍보 영상
16:05-16:20 국립면역학연구원 설립의 타당성
전창덕(대한면역학회 회장)
16:20-16:30 국립면역학연구원의 구조와 역할
최윤석(대한면역학회 기획위원장)
16:30-17:00 국립면역학연구원의 발전적 모델에 대한 공청회
TBA
17:00-17:15 폐회사 - 홍기종 (신변종 감염병 mRNA백신 사업단 단장)

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[Day 3] September 15 (Fri)
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
09:00-10:40 Symposium 5 - Mucosal Immunity
[Institute for Immunology and Immunological Diseases, Yonsei UniversityCollege of Medicine]*
Symposium 6 - Immunometabolism
[Innate Immune-Mediated Chronic Inflammatory Disease Medical Research Center]*
Chair June-Yong Lee (Yonsei University, Korea)
Changwan Hong (Pusan National University, Korea)
Chair Myung-Shik Lee (Soonchunhyang University, Korea)
Byung-Chul Oh (Gachon University, Korea)
09:00-09:25 Mapping uncharted landscapes of host-microbiota connectivity 09:00-09:25 Immunometabolic programs controlled by endoplasmic reticulum stress
Noah Palm (Yale University, USA) Juan Cubillos-Ruiz (Weill Cornell Medical College, USA)
09:25-09:50 Immune regulation of intestinal bacterial colonization 09:25-09:50 Immunometabolic checkpoints of inflammation and aging
Timothy Hand (University of Pittsburgh, USA) Vishwa Deep Dixit (Yale School of Medicine, USA)
09:50-10:15 The Critical Impacts of Tissue-Resident Helper T cells Following Respiratory Viral Infection 09:50-10:15 The role of adipose tissue immune cells in the regulation of systemic metabolism in obesity
Young Min Son (Chung-Ang University, Korea) Jongsoon Lee (Soongchunhyang University, Korea)
10:15-10:40 Intestine: central organ to maintain tolerogenic immunity 10:15-10:40 Roles of Immune Cells in Adipose Tissue and Energy Homeostasis
Seung Hyeok Seok (Seoul National University, Korea) Jae Bum Kim (Seoul National University, Korea)
10:40-11:00 Coffee Break Coffee Break
11:00-12:40 Symposium 7 - DC&Myeloid cells Symposium 8 - B cell & Humoral Immunity Meet the Editor
Chair Hun Sik Kim (University of Ulsan, Korea)
Je-Wook Yu (Yonsei University, Korea)
Chair You-Me Kim (KAIST, Korea)
Jinyong Choi (The Catholic University of Korea, Korea)
Chair Chong-Kil Lee (Chungbuk National University, Korea)
11:00-11:25 Impact of emergency granulopoiesis on metastatic dormancy in the bone 11:00-11:25 Clonal and cellular dynamics of the antibody response 11:00-12:40 Myths and legends in science publishing
Ilaria Malanchi (The Francis Crick Institute, UK) Gabriel D. Victora (The Rockefeller University, USA) Zoltan Fehervari (Nature Research, UK)
11:25-11:50 Uncovering the pathological role of innate immune regulators in lung and pancreatic inflammatory-related conditions 11:25-11:50 On Primary and Secondary Germinal Centers  
Brendan Jenkins (Hudson Institute of Medical Research, Austrailia) Garnett H. Kelsoe (Duke University, USA)
11:50-12:15 Time-controled DC activation for enhanced cancer immunotherapy 11:50-12:15 B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1
Yong Taik Lim (Sungkyunkwan University, Korea) Kihyuck Kwak (Yonsei Univerisity, Korea)
12:15-12:40 Epigenomic regulation of macrophages by inflammatory cytokines 12:15-12:40 Regulation of B cell Immune Responses by TFEB
Kyuho Kang (Chungbuk National University, Korea) You-Me Kim (KAIST, Korea)
12:40-13:30 Luncheon Symposium 4 - Lilly Korea Luncheon Symposium 5 - AbbVie Korea Luncheon Symposium 6 - Celltrion Pharm Inc.
Chair Seung Woo Han (Kyungpook National University, Korea) Chair Sang-il Lee (Gyeongsang National University, Korea) Chair Eun Young Lee (Seoul National University, Korea)
12:40-13:30 Exploring Inflammation, IL-17 and Effective Treatments for Pso, PsA, and axSpA 12:40-13:30 JAK inhibitor: New treatment option for ankylosing spondylitis patients 12:40-13:30 Clinical use of Remsima SC injection in rheumatoid arthritis and pondyloarthritis
Young-In Eom(Lilly Korea) Changnam Son (Eulji University, Korea) Hong Ki Min (Konkuk University, Korea)
13:30-14:30 Poster Presentation (Grand Ballroom C)
14:30-14:50 Coffee Break
14:50-16:30 Symposium 9 - Autoimmune Diseases
[Japanese Society for Immunology(JSI)]*
Symposium 10 - Cancer Immunology KAI Basic & Clinical Joint Academic Awardee lecture
Chair Wan-Uk Kim (The Catholic University of Korea, Korea)
Jong Hoon Kim (Yonsei University, Korea)
Chair Chan Hyuk Kim (KAIST, Korea)
Byung-Seok Kim (Incheon National University, Korea)
ChairJi Yun Noh (Korea University, Korea)
14:50-15:15 Using Artificial Intelligence to Understand Human In Situ Autoimmunity 14:50-15:15 LAG3: The Third Checkpoint Inhibitor 14:50-15:15 Award Ceremony
Marcus Clark (University of Chicago, USA) Dario A.A. Vignali (University of Pittsburgh, USA)
15:15-15:40 Genetics and functional genetics of autoimmune diseases 15:15-15:40 Programming of checkpoint blockade responsive T cells in infections and solid tumors 15:00-15:30 Role of cleaved cochlin for innate immunity in the bacteria-infected inner ear; Lesson from intravital imaging
Kazuhiko Yamamoto (RIKEN, Japan) Surojit Sarkar (University of Washington School of Medicine, USA) Young-Min Hyun (Yonsei University, Korea)
15:40-16:05 Inositol polyphosphate multikinase (IPMK) regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling 15:40-16:05 Blood-derived tumor-associated macrophages contribute to antitumor immunity against glioblastoma 15:30-15:40 Q&A
Seung-hyo Lee (KAIST, Korea) Heung Kyu Lee (KAIST, Korea)
16:05-16:30 The role of mitochondria in lupus 16:05-16:30 Toward Next-generation Engineered T cell Therapy
Jungsik Song (Yonsei University, Korea) Chan Hyuk Kim (KAIST, Korea)
16:30-16:50 Coffee Break
16:50-17:40 Plenary Lecture 3  
ChairKyungho Choi (Seoul National University, Korea)
16:50-17:40 Regulatory T cells as purveyors of immune tolerance
Alexander Rudensky (Memorial Sloan Kettering Cancer Center, USA)

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[Day 4] September 16 (Sat)
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
09:00-10:40 Young Investigator Session 1 Young Investigator Session 2 Clinical Immunology 1 (Korean Session)
Chair Young Sang Kim (Chungnam National University, Korea)
You Jeong Lee (Seoul National University, Korea)
Chair Pyeung-Hyeun Kim (Kangwon National University, Korea)
Jinwook Choi (GIST, Korea)
ChairSang-Kyu Ye(Seoul National University, Korea)
Hae Woong Choi (Korea University, Korea)
09:00-09:15 [OP-01] Mesenchymal stem cell-derived extracellular vesicles subvert the Th17 cell by destabilizing RORγt through post-translational modification 09:00-09:15 [OP-07] Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profiling 09:00-09:25 The intra-niche activation of clonal CXCL13+CD4+ T cells in tertiary lymphoid structures associated with non-healing blisters of pemphigus
Sunyoung Jung (Seoul National University, Korea) Saseong Lee (The Catholic University of Korea, Korea) Jong Hoon Kim (Yonsei University, Korea)
09:15-09:30 [OP-02] Altered self-antigen-mediated T cell immunity in rheumatoid arthritis 09:15-09:30 [OP-08] Dynamic coordination of innate immunity for enhanced cancer immunotherapy and reduction of immune cell exhaustion by using a kinetically activating nanoadjuvant
Jia Jia Lim (Monash University, Australia) Seung Mo Jin (Sungkyunkwan University, Korea)
09:30-09:45 [OP-03] Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity 09:30-09:45 [OP-09] Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors 09:25-09:50 Cimetidine enhances PD-1 blockade efficacy in melanoma by regulating PD-L1 expression on tumor
Jaeu Yi (Washington University, USA) Jin Gyu Cheong (Weill Cornell Medicine, USA) Kihyuk Shin (Pusan National University, Korea)
09:45-10:00 [OP-04] IL-15-driven homeostatic proliferation of progenitor exhausted CD8 T cells during persistent antigenic stimulation 09:45-10:00 [OP-10] A Gastrointestinal Type 2 Immune Circuit Regulates Responses to Dietary Fiber
Kyungmin Lee (Sungkyunkwan University, Korea) Do-Hyun Kim (Washington University, USA)
10:00-10:15 [OP-05] Unraveling the Role of 4-1BB-4-1BBL cis-Interaction in survival of activated self-reactive CD8+ T cells 10:00-10:15 [OP-11] Defects in aminoacyl-tRNA synthetase cause partial B and T cell immunodeficiency 09:50-10:15 Is Parkinson's disease an autoimmune disease?: The roles of α-synuclein specific T cells in the pathogenesis of Parkinson's disease
Rohit Singh (National Cancer Center, Korea) Ju A Shim (Pusan National University, Korea) Mingyo Kim (Gyeongsang National University, Korea)
10:15-10:30 [OP-06] A distinct CD8+ T cell subset derived from virtual memory T cells causes alopecia areata through innate-like cytotoxicity 10:15-10:30 [OP-12] Regulation of Interleukin-21 bioavailability critically controls germinal center B cell selection and differentiation. 10:15-10:40 Characteristics of eosinophils related to pathologic conditions
Joon Seok (Chung-Ang University, Korea) Zhian Chen (The University of Queensland, Australia) Ji-Hyang Lee (University of Ulsan, Korea)
10:30-10:40 Q&A 10:30-10:40 Q&A
10:40-11:00 Coffee Break
11:00-12:40 Symposium 11 - Innate Lymphocytes Symposium 12 - Microbiota & Immune Regulation Clinical Immunology 2 (Korean Session)
Chair Ji Hyung Kim (Korea University, Korea)
Seokchan Hong (University of Ulsan, Korea)
Chair Mi-Na Kweon (University of Ulsan, Korea)
Yun Kyung Lee (Soonchunhyang University, Korea)
Chair Chulwoo Kim (Korea University, Korea)
Su-Hyung Park (KAIST, Korea)
11:00-11:25 MAIT cells: development and functions 11:00-11:25 Commensal-specific T cells in host homeostasis and metabolism 11:00-11:25 Clinico-Immunological Studies in Korean Children with Inborn Error of Immunity (IEI)
Olivier Lantz (Institut Curie, France) Ivaylo Ivanov (Columbia University, USA) Ji-Man Kang (Yonsei University, Korea)
11:25-11:50 Novel regulation of ILC2s in type 2 airway inflammation 11:25-11:50 Development of microbiota specific T cells 11:25-11:50 Immune correlates of protection against COVID-19
Taylor Doherty (University of California, San Diego, USA) Gretchen Diehl (Memorial Sloan Kettering Cancer Center, USA) Sung-Han Kim (University of Ulsan, Korea)
11:50-12:15 ILCs as a new target for steroid-refractory disease 11:50-12:15 Fecal Microbes Combat Antibiotic-Resistant Pathogens in the Gut 11:50-12:15 AI-powered analysis of neoantigen and tumor microenvironment for cancer immunotherapy
Hye Young Kim (Seoul National University, Korea) Sang Sun Yoon (Yonsei University, Korea) Se-Hoon Lee (Sungkyunkwan University, Korea)
12:15-12:40 Dynamics of NK cell synapses 12:15-12:40 Role of the interaction between host gene and gut microbiome in the intestinal bowel disease 12:15-12:40 Immune determinants in tumor microenvironment for response of cancer immunotherapy
Junsang Doh (Seoul National University, Korea) Donghyun Kim (Seoul National University, Korea) Hye Ryun Kim (Yonsei University, Korea)
12:40-13:30 Luncheon Symposium 7 - Janssen Korea Luncheon Symposium 8 - Pfizer Korea Luncheon Symposium 9 - Moderna
Chair Seung Cheol Shim (Chungnam National University, Korea) Chair Sung-Hwan Park (The Catholic University of Korea, Korea) Chair You-Me Kim (KAIST, Korea)
12:40-13:30 The role of expectations of SIMPONI 100 mg mono in rheumatoid arthritis 12:40-13:30 JAK inhibition and risk factors for disease management 12:40-13:30 Present and future of mRNA vaccines
Min Jung Kim (Seoul Nation University, Korea) Naonobu Sugiyama (Pfizer Korea, Japan) Eui-Cheol Shin (KAIST, Korea)
13:30-15:10 Symposium 13 - Regulatory Immune Cells Symposium 14 - T cell Mediated Clinical Immunology
[Institute for Basic Science]*
 
Chair Seung-Ki Kwok (The Catholic University of Korea, Korea)
Yeonseok Chung Seoul National University, Korea
Chair Eui-Cheol Shin(KAIST, Korea)
Kihyuk Shin (Pusan National University, Korea)
13:30-13:55 A Regulatory T Cell Notch Code to License Tissue Inflammation 13:30-13:55 Improving immunologic outcome in myeloid leukemia by manipulating PD-1H/VISTA
Talal Chatila (Harvard Medical School,USA) Tae Kon Kim (Vanderbilt University, USA)
13:55-14:20 Lrig1-expression confers suppressive function to CD4+ cells and is essential for alleviating autoimmunity via the Smad2/3/Foxp3 axis 13:55-14:20 Recirculating tumor-specific T cell responses as biomarkers for human virally driven cancers
Sang-Kyou Lee (Yonsei University, Korea) Evan Newell (Fred Hutch, USA)
14:20-14:45 Check PD-1 on regulatory T cells in tumor 14:20-14:45 Heterogeneity of exhausted T cells and Treg cells in tumor microenvironment
Sang Jun Ha (Yonsei University, Korea) Su-Hyung Park (KAIST, Korea)
14:45-15:10 Role of iNKT cells in regulating skin inflammation 14:45-15:10 Epigenetic & Transcriptional regulation for enhanced CAR-T therapy
Seokmann Hong (Sejong University, Korea) Hyungseok Seo (Seoul National University, Korea)
15:10-15:30 Coffee Break Coffee Break
15:30-16:20 Plenary Lecture 4
Chair Yoontae Lee (POSTECH, Korea)
17:20-18:10 Molecular Mechanisms of CD8 T-Cell Exhaustion
E. John Wherry (University of Pennsylvania, USA)
16:20-17:00 Awards & Closing Ceremony (Room A)

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